TYRAMINE HYDROCHLORIDE FOR SYNTHESIS
- Part number
- RXSOL-60-6605-800
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Tyramine hydrochloride has been: coinfused with adenosine in control subjects and patients in order to reduce leg blood flow by 50% without affecting arterial blood pressure. labelled with fluorescence dyes (Atto 488 and Atto 655) to serve as a substrate for peroxidase in immunofluorescence analysis.Chemists synthesize chemical compounds that occur in nature in order to gain a better understanding of their structures. Synthesis also enables chemists to produce compounds that do not form naturally for research purposes. In industry, synthesis is used to make products in large quantity.
Applications
Characteristics and notes
A flowing future! A multistep, general flow chemistry protocol has been developed for the preparation of tyramine-based natural products. The process integrates room-temperature reactions with high-temperature Heck coupling reactions, where the heat has been supplied by microwave irradiation. As a proof of concept for ‘scaling out’ to attain larger quantities of the desired products, the four primary tyramine-based natural products were prepared on a gram scale using this synthetic protocol.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | : TYRAMINE HYDROCHLORIDE FOR SYNTHESIS |
| Part Number | : RXSOL-60-6605-800 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Sikka, Dahej, Hazira, JNPT, Goa, Mangalore, Cochin, Tuticorin, Chennai, Kakinada, Vizag, Paradip, Kolkata, UAE, Singapore.
| Phone | +91 22 27815540 / 41 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com | |
| Website | www.rxmarine.com |
| Name of Substance | Cas Number | EINECS No | Wt.% | Symbol |
| Ammonium Bisulphite | 60-19-5 |
200-462-5
|
10 -30 % | Xi |
| Ethanediol | 107-21-1 | 203-473-3 | 10 - 30% | Xn |
| Quaternary Ammonium Chloride | 68391-01-5 | 269-919-4 | 10 - 30% | C |
| Propan-2-ol | 67-63-0 | 200-661-7 | 1 - 5 % | Xi |
| Classification of the substance or mixture | Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008. |
| Label elements | No hazard pictogram, no signal word, no hazard statement(s), no precautionary statement(s) required |
| Other hazards | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| If inhaled | After inhalation: fresh air. |
| In case of skin contact | In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. |
| In case of eye contact | After eye contact: rinse out with plenty of water. Remove contact lenses. |
| If swallowed | After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell |
| Most important symptoms and effects, both acute and delayed | The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 |
| Indication of any immediate medical attention and special treatment needed |
No data available
|
| Suitable extinguishing media | Water Foam Carbon dioxide (CO2) Dry powder |
| Unsuitable extinguishing media | For this substance/mixture no limitations of extinguishing agents are given. |
| Special hazards arising from the substance or mixture | Carbon oxides Nitrogen oxides (NOx) Hydrogen chloride gas Combustible. Development of hazardous combustion gases or vapours possible in the event of fire. |
| Advice for firefighters | In the event of fire, wear self-contained breathing apparatus. |
| Further information | Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system. |
| Personal precautions, protective equipment and emergency procedures |
Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger
area, observe emergency procedures, consult an expert. For personal protection see section 8.
|
| Enviromental Precaution | Do not let product enter drains. |
|
Methods and materials for containment and cleaning up |
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dust |
| Reference to other sections | For disposal see section 13 |
| Precautions for safe handling | For precautions see section 2.2.For precautions see section 2.2. |
| Storage conditions |
Tightly closed. Dry.
|
| Storage class | Storage class (TRGS 510): 11: Combustible Solids |
| Specific end use(s) | Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| Control parameters | Ingredients with workplace control parameters |
| Personal Protection |
Eye protection : Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses Hand protection : Wear the following personal protective equipment: Standard glove type. Gloves should be discarded and replaced if there is any indication of degradation or chemical breakthrough. Skin protection : Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Sigma- T2879 Page 4 of 9 The life science business of Merck operates as MilliporeSigma in the US and Canada The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact
Material: Nitrile rubber Minimum layer thickness: 0,11 mm
Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers.It should not be construed as offering an approval for any specific use
scenari Respiratory protection : required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P1 The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. |
|
Control of environmental exposure
|
Do not let product enter drains. |
Gloves Suit
| Physical state | powder |
| Color | white, to, off-white |
| Odour | No data available |
| Melting point/freezing point |
Melting point/range: 271 - 274 °C - lit.
|
| Initial boiling point and boiling range |
No data available
|
| Flammability (solid, gas) | No Data Available |
|
Upper/lower
flammability or
|
No data available
|
| Flash point | No data available |
|
Autoignition
temperature
|
No data available |
|
Decomposition
temperature
|
No data available |
| pH | No data available |
| Viscosity | No data available |
| Vapor pressure |
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
|
| Water solubility | No data available |
| Partition coefficient: n-octanol/water | No data available |
| Vapor pressure | No data available |
|
Density No data available
Relative density
|
No data available |
|
Relative vapor
density
|
No data available |
|
Particle
characteristics
|
No data available |
| Explosive properties | No data available |
| Oxidizing properties | None |
| Other safety information | No data available |
| Recativity |
The following applies in general to flammable organic substances and mixtures: in
correspondingly fine distribution when whirled up a dust explosion potential may generally be assumed
|
|
Chemical stability
|
The product is chemically stable under standard ambient conditions (room temperature) . |
| Possibility of hazardous reactions |
No information available
|
| Incompatible materials |
No data available
|
|
Hazardous decomposition products
|
In the event of fire: see section 5 |
| Condition to Avoid |
Light.
no information available
|
|
Acute toxicity
|
Oral: No data available Inhalation: No data available Dermal: No data available |
| Skin corrosion/irritation |
No data available
|
| Serious eye damage/eye irritation | No data available |
| Respiratory or skin sensitization | No data available |
| Germ cell mutagenicity |
Test Type: Mouse Test system: lymphocyte Remarks: Mutation in microorganisms
Test Type: Mouse Test system: lymphocyte Remarks: Mutation in mammalian somatic cells.
|
| Carcinogenicity | No data available |
| Reproductive toxicity | No data available |
| Specific target organ toxicity - single exposure | No data available |
| Specific target organ toxicity - repeated exposure | No data available |
| Aspiration hazard | No data available |
| Endocrine disrupting properties Product: |
Assessment : The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: SJ6050000
To the best of our knowledge, the chemical, physical, and toxicological properties have notbeen thoroughly investigated.
|
|
Toxicity
|
No data available |
| Persistence and degradability | No data available |
|
Bioaccumulative potential
|
No data available |
| Mobility in soil | No data available |
|
Results of PBT and vPvB assessment
|
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Endocrine disrupting properties Product: |
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
|
| Other adverse effects | No data available |
| Waste treatment methods Product | See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions. |
Hazard Pictograms:
| UN Number | ADR/RID: - IMDG: - IATA: - |
| UN proper shipping name |
ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
|
| Transport hazard class(es) 8 | |
| ADR/RID |
ADR/RID: - IMDG: - IATA: -
|
| Packing group | |
| Packing group | IIIADR/RID: - IMDG: - IATA: - |
| Environmental hazards | |
| Environmental hazards | ADR/RID: no IMDG Marine pollutant: no IATA: no |
| Special precautions for user |
No data available
|
| Further information |
Not classified as dangerous in the meaning of transport regulations.
|
|
Safety, health and environmental regulations/legislation specific for the
substance or mixture
|
This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. |
| Chemical safety assessment |
For this product a chemical safety assessment was not carried out
|
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages. DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |
